A Motivation Letter That Stands Out

As someone currently reviewing applications for an open postdoc position, I’ve been reading a lot of motivation letters lately. Some are excellent. Others… could use a bit more thought. So I wanted to share a few reflections on what makes a strong motivation letter — and what to avoid.

A motivation letter (or cover letter) is your one chance to stand out from several dozen applicants. With a high number of submissions, the time spent on each letter is limited. That means your letter needs to be clear, relevant, and easy to follow — ideally structured in a way that helps the reader quickly understand who you are, why you’re applying, and what you bring to the table.

Here’s a structure that often works well:

1. What are you applying for, and who are you?
Start with a short paragraph stating the position you’re applying for and a brief introduction to your background.
Example: “I am currently completing my PhD in molecular biology at X University, where I focus on Y.”

2. Why this position and this group?
Explain what excites you about the topic and why you want to join this specific lab. Be specific. Mention a recent paper or project that caught your attention — but make sure it’s actually from the group (not a collaboration where the key method was done elsewhere). The lab’s homepage is also a great resource.

3. What do you want to learn?
Show that you’ve done your homework. What skills or knowledge are you hoping to gain? For example: “I’m particularly interested in learning more about single-cell transcriptomics and how it can be applied to study X.”

4. What can you contribute?
Do you have a specific technical skill that fits the project? Or soft skills like communication or teamwork? Add a short example.
Example: “During my PhD, I co-organized a seminar series that brought together researchers from different departments, which helped me develop strong coordination and communication skills.”

5. Use keywords from the job ad
This helps your application stand out during a quick read-through. It also shows that you’ve paid attention to the actual requirements and expectations.

6. Submit through the correct channel
If there’s an online system, use it. Personally, I only start reviewing applications after the deadline and only through the system.

Additional Tips

7. Show genuine interest
Avoid generic phrases like “I am passionate about science.” Instead, show your interest through specific examples or reflections on the group’s work.

8. Be honest and realistic
It’s okay to say you want to learn something new — just be clear about what you already know and what you hope to gain. Overpromising can backfire.

9. Proofread carefully
Typos, grammar mistakes, or formatting issues can distract from your message. Ask someone to read it over before submitting.

10. Keep the tone professional but personal
You’re writing to a future colleague, not a faceless institution. Be respectful, but let your personality and enthusiasm come through.

11. Include contact details if requested
If the job ad asks for reference persons or contact info, make sure it’s included and clearly formatted.